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Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4

    Buy cheap Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4 from wholesalers
     
    Buy cheap Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4 from wholesalers
    • Buy cheap Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4 from wholesalers

    Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4

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    Brand Name : World Caring, active pharmaceutical ingredient
    Certification : COA
    Model Number : C-045
    Price : negotiable
    Delivery Time : 7days
    Payment Terms : T/T, Western Union, Paypal
    Supply Ability : 5000kgs per month
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    Active Pharmaceutical Ingredient 99% purity Entecavir /CAS 142217-69-4


    Active Pharmaceutical Ingredient 99% purity Enticavir /CAS


    142217-69-4


    Specifications:


    Name:Enticavir

    Synonyms : 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one

    Molecular Formula : C12H15N5O3

    Molecular Weight : 277.28
    CAS:142217-69-4


    Uses:


    Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir is a nucleoside analog (more specifically, aguanosineanalogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. The drug's manufacturer claims that entecavir is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection.


    Certificate of Analysis


    Items

    Specifications

    [Description ]

    It should be white or whitish crystalline powder, odorless and tasteless, very slightly in water, slightly soluble in methanol and insoluble in ether.

    Specific rotation

    Should be between +24°~+28°

    [Identification]

    (1) HPLC

    Retention time of the principal peak obtained from the test solution should be identical with that of the reference solution.

    (2) IR

    IR spectrum of samples should be identical with that of the reference standard.

    [Test]

    pH

    Should be between 5.5~7.5

    Related substances

    (1)Total impurity

    Should be 0.3%max

    (2)maximum single impurity

    Should be 0.1%max

    Enantiomer

    Should be 0.2%max

    Methanol

    Should be 0.3%max

    Dichloromethane

    Should be 0.06%max

    N- hexane

    Should be 0.029%max

    Tetrahydrofuran

    Should be 0.072%max

    N,N-dimethylformamide

    Should be 0.088%max

    Toluene

    Should be 0.089%max

    Water

    Should be between 5.8%~6.5%

    Residue on ignition

    Should be 0.1%max

    Heavy metal

    Should be 20ppmmax

    Assay

    98.0%~102.0%(C12H15N5O3) calculated on anhydrous basis


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