Bioneovan Rapid test for IgM Antibody to Mumps virus(Colloidal
Gold) is an in vitro immunoassay for the qualitative determination
of the detection of mumps virus IgM antibodies in human whole
blood, serum or plasma samples, and is used as an auxiliary
diagnostic reagent for early infection of mumps virus in clinical
diagnosis.
SUMMARY
Mumps Virus (Mu) is a pathogen of mumps, belonging to the
Paramyxoviridae family. It was first discovered in 1935 and proved
to be the main cause of mumps. The popularity of MuV is peaked in
winter and spring, and is limited to humans. MuV is the only source
of infection for infected people. The main routes of transmission
are saliva, saliva-contaminated foods and articles, and airborne
droplets. Children and adolescents are susceptible to mumps.
Clinical take parotid gland enlargement as main characteristic,
common complication has virus meningitis and encephalitis,
orchitis, epididymis inflammation, still have ovarian inflammation,
pancreatitis, myocarditis to wait in addition, it is the male
infertile disease and child acquired sex deaf most common reason,
serious person can bring about disable or death. Mumps virus IgM
antibody appeared shortly after the onset (2 ~ 3 days), and reached
a peak within 2 weeks, and then decreased gradually, which could be
kept for several months, and was an important basis for early
diagnosis of MuV infection.At present, the main methods to diagnose
MuV infection in clinic or laboratory include virus isolation and
culture, serological detection (complement binding test,
neutralization test, etc.), immunological detection (enzyme-linked
immunoassay, indirect immunofluorescence detection, etc.) and
molecular biological methods such as rt-pcr.
SAMPLE REQUIREMENT
1. Serum samples are collected by intravenous method according to
the conventional method; plasma sample processing method: 1%
heparin solution 100 μL anticoagulation 5-10 mL blood, 3.8% sodium
citrate solution and blood anticoagulation in a ratio of 1:9, 15%
0.04 mL of disodium edetate (EDTA) solution was anticoagulated with
5 mL of blood.
2. Serum or plasma samples can be stored within 5 days after
collection, and can be stored at 4 °C. For samples larger than 5
days, samples should be stored at -20 °C. The number of freeze-thaw
cycles should not exceed 3 times. .
3. Whole blood samples are recommended to be tested within 3 days.
The sample is stored at 2~8 °C. Do not freeze.
4. Hemolysis sample test results are invalid.
