Epigallocatechin Gallate /EGCG 95% ·
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Product Details:
Prodcut name: Muscle-building Epigallocatechin Gallate /EGCG 95%
/green tea extract
Synonym:(2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol3-(3,4,5-trihydroxybenzoate)
Molecular formulas : C22H18O11
Molecular weight : 458.38
Appearance: off-white color powder
CAS number: 989-51-5
Used Part: Leaf
Grade: Food & Pharmaceutical
Test Method: HPLC
Epigallocatechin gallate (EGCG), also known as
epigallocatechin-3-gallate, is the ester of epigallocatechin and
gallic acid, and is a type of catechin.
EGCG, the most abundant catechin in tea, is a polyphenol under
basic research for its potential to affect human health and
disease. EGCG is used in many dietary supplements.
It is found in high content in the dried leaves of white tea (4245
mg per 100 g), green tea (7380 mg per 100 g) and, in smaller
quantities, black tea. During black tea production, the catechins
are mostly converted to theaflavins and thearubigins. via
polyphenol oxidases.
EGCG is a kind of component extracted from Chinese green tea. It is
the primary active and water-soluble component of green tea, which
has the highest content among the tea catechins. By virtue of its
peculiar stereochemical structure, EGCG possesses much stronger
anti-oxidant activities and plays an important role in preventing
cancer and cardiovascular diseases. In addition, it is potent as
the reversal agent of MDR (Multidrug Resistance). As such, it may
improve the sensitivity of cancer cells to chemotherapy drugs and
reduce toxicity on the heart.
| Analysis | Specification | Result | Test method |
| Assay (egcg) | 95.0% Min | 95.12% | HPLC |
| Appearance | Off white powder | Complies | Visual |
| Part Used | Leaf | Complies | Visual |
| Extract Solvent | Ethanol & Water | Complies | Visual |
| Particle size | 100% through 80 mesh | 80 mesh | 80 Mesh Screen |
| Bulk Density | 40.0~65.0 g/100m | 49.1g/100mL | Complies |
| Loss on drying | 5% Max | 2.55% | 5g / 105℃/5hrs |
| Ash Content | 5% Max | 2.13% | 2g / 600℃ /3hrs |
| Heavy metals | 10ppm Max | Complies | AAS |
| As | 1ppm Max | Complies | AAS |
| Microbiology | | | |
| Total plate count | 1000cfu/g Max | Complies | AOAC |
| Yeast & Mold | 100cfu/g Max | Complies | AOAC |
| E. Coli | Negative | Negative | AOAC |
| Salmonella | Negative | Negative | AOAC |
EGCG is the major component of the polyphenolic fraction of green
tea. It makes up about 10-50% of the total green tea catechins
includeing epigallocatechin gallate (EGCG), epigallocatechin (EGC),
epicatechin gallate(ECG), epicatechin(EC), gallocatechin gallate
(GCG), catechin are major catechin of green tea catechin. The
antioxidant activity increased in the following order:
EC<ECG<EGC<EGCG.
Many studies indicate EGCG plays a role, which protects aganist
free-radical DNA damage, protects aganist the effects of ionizing
radiation and ultraviolet radiation, inhibits lipid peroxidation,
decreases serum cholesterol levels, LDL, VLDL and triglycerides,
interferes with the binding of cancer-causing agents to cellular
DNA, helps to neutralize dietary carcinogens, works with enzymes
and other antioxidants in the intestine, liver and lungs to prevent
the activation of certain carcinogens before they damage DNA. As a
free radicals scavenger, EGCG combats the effects of pollution,
sunlight and smoking, helps skin from wrinkling and aging.
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