Hot Sale Natural Product Feverfew Flower P.e
| Product Name: | Natural Feverfew extract |
| Latin Name: | chryanthemum parthenium |
| Specification: | 0.3%, 0.8% parthenolide |
| Appearance: | Brown fine powder |
| Extract Part: | Aerial part |
| Extraction Type: | Solvent Extraction |
Brief Introduction:
Feverfew has had a long history of medicinal use. Steven Foster,
one of America's most eminent herbalists, points out in his
excellent monograph on feverfew that Dioscorides, a first century
Greek physician, recommended it over 1900 years ago.Foster further
informs us that feverfew has been used throughout the world in
various cultures in a number of other ways. It has been used as a
carminative (relieves stomach problems-gaseous distention and
flatulence), emmenagogue (substance which promotes menstrual
discharge), tonic, vermifuge (expeller of parasitic worms), and
anti inflammatory agent for arthritis. It has also been used for
the treatment of kidney pain, vertigo, and relief from morning
sickness.Parthenolide content.
A strongly aromatic perennial, feverfew bears a daisy-like disc, or
head, of strongly crowded bisexual yellow flowers with a single row
of white ray florets. Two well publicized British studies, one
conducted at the City of London Migraine Clinic in collaboration
with Chelsea College , and the other at Nottingham's University
Hospital , used material conforming to this description. Dried
leaf, acquired from the Chelsea Physic Garden with a parthenolide
(asesquiterpene lactone thought to be the active ingredient) at a
concentration of 0.42%, was used in the London clinical trial.
However, it should be noted that the parthenolide content varies in
the three or four varieties available and that the greatest
percentage of parthenolide is not to be found in the leaves of the
variety chosen for the British studies but in a form (T. parthenium
flosculosum) without ray florets.
Product Name | Feverfew Extract |
CAS NO. | 20554-84-1 |
Molecular Formula | C15H20O3 |
Molecular Weight | 248.32 |
Appearance | Brown powder |
Odor & Taste | Characteristic |
Assay(HPLC/UV) | Parthenlide 0.4%,0.8%,1.5%,3% |
Loss on Drying | ≤5.0% |
Ignition Residue | ≤5.0% |
Sieve Analysis | ≥100mesh |
Extract Solvent | Ethanol |
Residual Solvent | ≤0.5% |
Heavy Metal | ≤10ppm |
Total Plate Count | <1000cfu/g |
Yeast & Mold | <100cfu/g |
E.Coil | Negative |
Salmonella | Negative |
Storage | Store in cool & dry place. Keep away from strong light and heat. |
Main Function:
1.Modulation of the NF-κB-mediated inflammatory responses in
experimental atherosclerosis.
2.Inducing apoptosis in acute myelogenous leukemia (AML) cells,
leaving normal bone marrow cells relatively unscathed. Moreover,
the compound may get at the root of the disease because it also
kills stem cells that give rise to AML.Parthenolide is under
consideration as a potential cancer drug in combination with
sulindac.
3.Activity against a parasite Leishmania amazonensis.
4.Microtubule-interfering activity.
5.Anti-inflammatory and anti-hyperalgesic effects.
6.Blocking lipopolysaccharide-induced osteolysis through the
suppression of NF-κB activity.
7.Inducing apoptosis and production of reactive oxygen species in
high-risk pre-B leukemia cells.
