Kit for Determination of Zinc Levels in Seminal Plasma
Male Infertility Diagnosis
The kit is mainly used for quantitative detection of zinc
concentration in human seminal plasma,while also used to determine
the zinc concentrationin blood, body fluid, food and other types of
specimens.
Features:
- It is the first one in the country domestic that adopts the method
recommended by WHO to produce the kit. And thisItbreaks the
monopolization of Wako Company in the technology. Thus BRED has been the second producer
manufacturerof using this technology in the world.
- With good-specificity, sensitivity and stability of the test
results. Convenient to handle.
- Operationed in the microplate. Fast and easy-to-use.
- Available for automatic and semiautomatic tests, good to make for
standardization of test.
- It is ready for use and easy to handle.
- 40 tests per kit and meet the need of batch testing.
Applications in clinic:
Zinc is one of the indicators of functional evaluation indicators
for prostate, which is associated with the antibacterial infection.
The pathogenic microorganism infections may cause the male
prostatitis, with the appearance ofed asdelayed liquefactionof
semen and decrease of zinc level in seminal plasma.
The production, maturation, activation and capacitation of sperm
require the participation of zinc. The lack of zinc in seminal
plasma may cause the decrease of sperm motility; the zinc level is
correlated with the depolymerization function of nuclear chromatin;
. Mmaintainence in the normal zinc levelsin the semen would prevent
the underlying damage to sperm of the male/female genital tracts; .
Zinc is also one of metals contained in the superoxide dismutase
(SOD), which can remove the free radicalscontained in the semen
plasma, thereby thereforeinhabiting preventing the lipid
peroxidation of cell membrane and protecting the morphosis and
functions of sperm against the damage.
Long-termtimezinc deficiency would directly influence the feedback
mechanisms of pituitarium, and lead to the testicular hypoplasia
and hypogonadism. Furthermore, zinc also plays an essential role in
the regulation of androgen metabolism, and decrease in zinc
levelsmay promote the conversion of testosterone to
dihydrotestosterone.
Reference:
World Health Organization.WHO Laboratory Manual for the Examination
of Human Semen and Sperm-Cervical Mucus Interaction (4th
edition),2001.
