Albumin powder GHL High speed Wet Mixing Granulator Machine (High shear granulation) (Granulating machine)( Granulating equipment, granulation equipment, Bottom-Drive Granulator);

Preface

YIBU” considers that the machine adopts horizontal cylinder structure, its structure reasonable. Air filled seal shaft for to drive. When washed , it can be changed to water. Fluidized Granulation, the granule is around ball shape. Its flow ability is good. Compared to traditional process, 25% of adhesive can be reduced and the drying time is short. The dry mixing time is 2 minutes and the granulating time is 1-4 minutes. Compared to the traditional process , 4-5 times of efficiency is raised.

Dry mixing ,humid mixing and granulating are finished in the same sealed container. It is in conformity with the requirements of GMP. The whole operation has strict safe and protective measures. Jacket type might be adopted on request

We have manufactured decades specifications and 150 different machines to meet different needs. These practical experiences will be very beneficial to customers.

High process efficiency through extremely fast drying and gentle product handling. Suitable for batches of 10 to 800Liter per batch .Further batch sizes available upon request；

Principle :

High shear granulation in a closed container with blending tools driven from above or below has long been applied by the pharmaceutical industry. The mechanical effect of the blending tools – irrespective of whether in batches or continuous operation – creates a denser granulate than the fluidized bed process.

Originally, the granulation liquid was poured into the product. Today, an improved dosed distribution using a spray nozzle is preferred in order to obtain a more even granulate.

The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.

The electronic systems and their safety should comply with the requirements set forth in 21 CFR Part 11 and GMP Annex 11;

The data should be collected at appropriate time intervals and stored in the system in a fixed format that can be printed out/read;

Changzhou Yibu Drying Equipment Co., Ltd. is a leading manufacturer of drying, mixing, and granulating equipment in China, a specially-designated enterprise of China Association for Pharmaceutical Equipment (CAPE) and China General Machinery Industry Association (CGMA) Drying Equipment Branch. The factory covers an area of over 50,000 m2, has fixed assets of CNY 35 million, with more than 180 sets of special processing equipment and strong technical force. The company owns the provincial famous trademark of "YIBU", and has passed the ISO9001 & ISO14001 certifications.
The founder, Mr Zha Guocai has devoted more than 30 years in R&D, production and business of drying equipment. He holds the post of Deputy Director-General of China General Machinery Industry Association (CGMA) Drying Equipment Branch for a long time. The company pays great attention to science and technology innovation, has collaborated with Medicine Design Institutes in Shanghai, Wuhan, Chongqing and other places, Shenyang Chemical Research Institute, Qinghua University, Shanghai Jiaotong University, Dalian University of Technology, etc. The company launched 3-5 new products to the market every year. In 1998, YIBU established "China Research Center of Drying and Granulating" with the approval of relevant state department, and cooperated with pharmaceutical, chemical and food industries to research and develop new technologies related to drying, granulating and mixing, etc. The factory also has a variety of test prototypes in the laboratory for customers' trials.
The company sold equipment to USA, Mexico, Columbia, Guatemala, Brazil, Peru, Australia, New Zealand, Ghana, Russia, Cyprus, Greece, Iran, Indonesia, Philippines, Korea, Japan, Taiwan, Hong Kong and other countries.