100% Natural Apple Root Extract Phloretin
1.Product Profile
Specification: Phlorizin 98%
CAS NO: 60-81-1
Purity:≥98%
Molecular formula:C21H24O10
Molecular weight: 436.41
Appearance; Light yellow acicular crystal
Test Method: HPLC
Place of Origin: China(Mainland)
Plant Name: Malus pumila Mill
Plant Source: Apple root bark, stems
2.What is Apple Extract Phlorizin?
Phlorizin is naturally occurring in some plants. It could be found
in the bark of pear (Pyrus communis), apple, cherry and other fruit
trees (Rosaceae) and is responsible for the petal color in Dianthus
caryophyllus.
Phlorizin is a white to yellow crystalline solid with a melting
point of 106–109 °C. It is of sweet taste and contains four
molecules of water in the crystal. Above 200 °C, it decomposes. It
is poorly soluble in ether and cold water, but soluble in ethanol
and hot water. Upon prolonged exposure to aqueous solutions
phlorizin hydrolyzes to phloretin and glucose.
Phlorizin is a competitive inhibitor of SGLT1 and SGLT2; this
reduces renal glucose transport, lowering the amount of glucose in
the blood. Phlorizin was studied as a potential pharmaceutical
treatment for type II diabetes, but has since been superseded by
more selective and more promising synthetic analogs, such as
canagliflozin and dapagliflozin.
3.Specification
| Item | Specification | Result | Test Method |
| Physical Control |
| Appearance | Fine Powder | Complies | Visual |
| Color | Yellow-brown | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Taste | Characteristic | Complies | Organoleptic |
| Sieve Analysis | 100% thru 80 mesh | Complies | 80 Mesh Screen |
| Loss on Drying | 5% Max | 3.68% | CPh |
| Ash | 5%Max | 4.26% | CPh |
| Solubility | Good Solubility in water | Complies | Organoleptic |
| Chemical Control |
Heavy metals | NMT 10ppm | Conforms | Atomic Absorption |
| Arsenic (As) | NMT 1ppm | Conforms | Atomic Absorption |
| Mercury(Hg) | NMT 2ppm | Conforms | Atomic Absorption |
| Lead (Pb) | NMT 2ppm | Conforms | Atomic Absorption |
| GMO Status | GMO Free | Conforms | / |
| Pesticides Residues | Meeting USP Standard | Conforms | Gas Chromatography |
| Microbiological Control |
| Total Plate Count | 10000cfu/g Max | Conforms | AOAC |
| Yeast & Mold | 300cfu/g Max | Conforms | AOAC |
| E.Coli | Negative | Negative | AOAC |
| Salmonella | Negative | Negative | AOAC |
| Staph Aureus | Negative | Negative | AOAC |
4.Where will Apple Extract Phlorizin be used for?
1. Slow the growth of cancer cells and tumors and promote cancer
cell death. Prevent skin, breast and colon cancer, and lower the
risk of colon and lung cancer;
2. Effect against external aging by promoting the health of skin
cells and rejuvenation. Effect the Internal aging by promoting
organ health, destroying the free radicals and strengthening
fibers;
3. Reduce the number of atherosclerotic lesions in arteries, the
amount of cholesterol produced in the liver and uric acid content
in the blood.
5.Function of Apple Extract
1. Improve the body's resistance to fight against diseases.
2. Prevent oxidative stress.
3. Reduce fat around body organs.
4. Build strong muscles
5. Provide nutrition to the body.
6. Improve skin problems and skin disorders.
7. Assist in solving the problem of baldness in males.
8. Fight heart diseases.
