EDTA Blood Collection Tube with Precise Anticoagulation

I. Product Characteristics

EDTA blood collection tubes (purple cap) utilize dipotassium or tripotassium ethylenediaminetetraacetate (EDTA-K₂ or EDTA-K₃) as the core anticoagulant, featuring:

1. Precise Anticoagulation Mechanism: Chelates calcium ions (Ca²⁺) in blood to block thrombin activation, achieving complete anticoagulation while maximally preserving blood cell morphology.

2. Optimized Physical Design:

   • High-transparency PET plastic or glass tube with mechanical strength and light resistance;

   • Pre-filled precise anticoagulant dosage (1.5–2.2 mg EDTA/mL blood), vacuum accuracy ≤±5%.

3. Safety & Quality Control:

   • Gamma-irradiated sterilization (8–25 kGy), controlled endotoxin levels;

   • ISO13485/CE compliant; standardized purple cap for rapid identification.

II. Application Scenarios

Primarily for hematological testing, with specific applications:

Note: EDTA tubes cannot be used for electrolyte, trace element, or coagulation testing due to chelation interference.

III. Usage Protocol & Specifications

IV. Precautions

1. Anticoagulant Risks:

   • Overfill (>2.2 mg/mL): RBC shrinkage/platelet swelling → morphology distortion;

   • Underfill: Inadequate anticoagulation → microclots → instrument obstruction.

2. Sample Handling:

   • Do not reuse tubes or mix additives;

   • Blood volume ≤ labeled capacity (e.g., ≤5.5 mL for 5 mL tube).

3. Safety:

   • EDTA is corrosive; rinse skin/eyes immediately with water if contacted.

V. FAQs

1. EDTA-K₂ vs. EDTA-K₃?

   • Solubility: K₃ dissolves easier → liquid pre-filled tubes; K₂ → spray-dried plastic tubes;

   • Performance: Comparable anticoagulation, but K₃ excess may cause platelet satellitism (pseudothrombocytopenia).

2. Causes of Pseudothrombocytopenia? Solutions?

   • Causes: EDTA-induced platelet aggregation (~0.1% incidence) or neutrophil adhesion (satellitism);

   • Resolution: Recollect using sodium citrate tube.

3. Can tubes with microclots be used?
   → No. Microclots indicate anticoagulation failure → recollect with thorough mixing.

4. Suitable for glucose testing?
   → Compatible with sodium fluoride (2–4 mg/mL blood) to inhibit glycolysis; validate system compatibility.

Clinical Note: EDTA tubes remain the gold standard for CBC. For abnormal cases (e.g., suspected platelet disorders), parallel testing with alternative anticoagulants is recommended.

Shanghai Orsin Medical Technology Co., Ltd. is located in No. 599, Wanhua Road, Zhelin Town, Fengxian District, Shanghai. Is China's production of one-time vacuum collection of professional companies, Shanghai Medical Device Industry Backbone Enterprises. The product takes Orsin pattern as the registered trademark.

Since its inception, has always been Advanced Equipment, Smiling Service, Rigorous Attitude, Perfect Products to serve the industry. With excellent quality and excellent service, in more than 500 hospitals at all levels and hundreds of medical institutions in the clinical use of medical laboratory has won the unanimous recognition and praise.

A variety of Vacuum Blood Tubes containing different additives, such as EDTA, Sodium Citrate, Heparin, Glucose, Clot Activator, etc. With its safe, effective, fast and accurate characteristics to fill the domestic blank, much favored. Orsin has in the provinces and cities with offices or agents, to provide customers with fast and thoughtful after-sales service.