GMP Negative Pressure Weighing Booth | H14 HEPA Filtration | Dust Containment System

GMP Negative Pressure Weighing Booth | H14 HEPA Filtration | Dust Containment System

Engineered for precise material handling in pharmaceutical production, this weighing booth prevents cross-contamination while maintaining GMP-compliant environmental conditions. Ideal for potent compound weighing and dispensing operations.

Product Features

1. Advanced Containment Technology

• Negative pressure design: Maintains -15Pa to -30Pa gradient to prevent dust escape

• Triple-stage filtration: Combines G4→F8→H14 filters for 99.995% particle retention

2. Precision Process Control

• Dual 1.5KW fans: Ensure stable airflow (0.45±0.1m/s) during material transfers

• Real-time monitoring: Touchscreen displays differential pressure, wind speed, and filter status

3. GMP-Compliant Construction

• 304 stainless steel: Resists disinfectants and prevents particle shedding

• Seamless welds: Eliminate contamination traps per EU GMP Annex 1

4. Operational Safety

• Automatic alarms: Trigger for pressure deviations or filter saturation

• Emergency stop: Instantly halts operations if containment is compromised

Application Scenarios

1. Potent Compound Handling

• Contains cytotoxic dust during oncology drug dispensing (USP <800> compliant)

2. API Weighing

• Maintains ISO 8 conditions for active pharmaceutical ingredient measurement

3. Excipient Preparation

• Prevents cross-contamination in multi-product facilities

4. Sterile Formulation

• Protects sterile cores during tablet compression line feeding

5. R&D Laboratories

• Enables safe handling of experimental compounds in early development

Technical Validation

• Filter Efficiency: EN 1822-5:2009 tested at MPPS (0.12-0.25μm)

• Pressure Control: Validated per ISO 14644-3 Annex B4

• Material Compliance: ASTM A240 304 stainless steel, Ra ≤0.5μm

FQAs

Q1: How does the negative pressure system prevent hazardous powder exposure?
The booth maintains -15Pa to -30Pa pressure gradient with dual 1.5KW fans, creating inward airflow that contains 99.9% of particles ≥5μm. This exceeds OSHA 29 CFR 1910.134 requirements for hazardous drug handling.

Q2: What makes your H14 filter more effective than standard HEPA?
Our MRJH H14 filters are MPPS-tested at 0.12μm (vs standard 0.3μm), capturing 99.995% of particles - critical for potent compounds like cytotoxics. Includes DOP test ports for routine validation.

Q3: Can the system handle continuous weighing of multiple APIs?
Yes, the 304 stainless steel interior and flow equalization membrane prevent cross-contamination during product changeovers. Touchscreen logs each session for 21 CFR Part 11 compliance.

Shenzhen Meiri Purification Technology Co. Ltd., known by our brand "MRJH," is a leading manufacturer of cleanroom equipment based in Shenzhen, China. With a spacious facility spanning over 30,000 square meters, we specialize in the research, development, production, sales, and service of professional cleanroom solutions.

At MRJH, we offer a wide range of high-quality products to meet your purification needs. Our product lineup includes Fan Filter Units, Pass Boxes, Air Showers, Cargo Showers, laminar flow hoods, HEPA Box, HEPA Filter , Clean Room Filters , steel doors, and various other clean room equipment. We take pride in our ability to provide OEM/ODM/customized services to tailor our products to your specific requirements.

Since our establishment in 2012, we have been committed to delivering exceptional air filters, air purification equipment, and cleanroom solutions. Our state-of-the-art production facilities are equipped with advanced AMADA CNC punching machines, CNC bending machines, shearing machines, and large laser machines. These cutting-edge technologies enable us to maintain stringent quality control and ensure the precision and reliability of our products.

At MRJH, we prioritize customer satisfaction and strive to provide solutions that meet international standards. Our friendly and professional team is dedicated to delivering outstanding service and support throughout the entire process. We are proud to serve clients globally and look forward to partnering with you to create a cleaner and safer environment.

Please feel free to contact us for any inquiries or further information.