DOA K2 rapid Test with CE certificate urine uncut sheet
For professional in vitro diagnostic use only.
| Product Name | K2 One Step Synthetic Cannabis Test |
| Formats | Strip(3mm)Device(4mm) uncut sheet |
| Place of Origen | China |
| Specimen | Urine |
| Read Time | 5 minutes |
| Shelf life | 2 years |
| Package | uncut sheet |
| Storage | 2℃-30℃ |
INTENDED USE
The One Step Synthetic Cannabis Test is a lateral flow chromatographic immunoassay for the
detection of Synthetic Cannabis JWH-018 Pentanoic Acid and /or
JWH-073 Butanoic Acid at the cut-off level of 25ng/ml
The assay is intended to verify an intoxication in patients. It
provides a qualitative, preliminary analytical test result. A more
specific alternate chemical method must be used in order to obtain
a confirmed analytical result. Gas chromatography/mass spectrometry
(GC/MS) is the preferred confirmatory method. Clinical
consideration and professional judgment should be applied to any
drug of abuse test result, particularly when preliminary results
are positive.
PERFORMANCE CHARACTERISTICS
A.Sensitivity
One Step Synthetic Cannabis (K2) Test has set the screen cut-off
for positive specimens at 25 ng/mL for JWH-018 Pentanoic Acid and
JWH-073 Butanoic Acid as the calibrators. The test device has been
proved to detect above the cut-off level of the target drugs in
urine at 5 minutes.
B. Specificity and cross reactivity
To test the specificity of the test, the test device was used to
test Synthetic Cannabis (K2), its metabolites and other components
of the same class that are likely to be present in urine, All the
components were added to drug-free normal human urine. These
concentrations below also represent the limits of detection for the
specified drugs or metabolites.
Component Concentration (ng/ml)
| JWH-018 Pentanoic Acid | 25 |
| JWH-073 Butanoic Acid | 25 |
| JWH-018 N-4-hydroxypentyl | 2,000 |
| JWH-018 (Spice Cannabinoid) | 1,000 |
| JWH-018 4-Hydroxypentyl metabolite-D5 (indole-D5) | 1,000 |
| JWH-073 (Spice Cannabinoid) | 2,000 |
| JWH-073 3-Hydroxybutyl metabolite | 1,000 |
| JWH-073 3-Hydroxybutyl metabolite-D5 (indole-D5) | 1,000 |
| JWH-019 6-hydroxypentyl | 1,000 |
| JWH-122 N-4-hydroxypentyl | 2,000 |
| JWH-210 5-Hydroxypentyl metabolite | 5,000 |
| AM2201 4-Hydroxypentyl metabolite | 1,000 |
C. Interfering substances
Considering the complexity of clinical urine specimens and the
possibility that various urine specimens contain potentially
interfering substances, for example Acetaminophen, Biotin, Glucose
etc., we simulated above situations by adding the potentially
interfering substances to a certain concentration as specimen.
SUMMARY
Synthetic cannabis is a psychoactive designer drug created by
spraying natural herbs with synthetic chemicals that, when
consumed, allegedly mimic the effects of cannabis. It is very well
known under the K2 and Spice brand names. Synthetic cannabis
contained synthetic cannabinoids which act on the body in a similar
way to cannabinoids naturally found in cannabis, such as THC. A
large and complex variety of synthetic cannabinoids, most often
cannabicyclohexanol, JWH-018, JWH-073, or HU-210, are used in an
attempt to avoid the laws that make cannabis illegal, making
synthetic cannabis a designer drug. Although synthetic cannabis
does not produce positive results in drug tests for cannabis, it is
possible to detect its metabolites in human urine.
