Infectious disease diagnostic Hepatitis B e Antgen(HBeAg) for Closed Automatic immunoassay analyzer in Infectious Diseas

Infectious disease diagnostic Hepatitis B e Antgen(HBeAg) for Automatic immunoassay analyzer in Infectious Disease

This product is used to quantitatively detect the content of hepatitis B virus e antigen in human serum or plasma in vitro.

Hepatitis B virus e-antigen (HBeAg), commonly known as e-antigen. HBeAg is a soluble component of the core antigen, which is a marker of hepatitis B infectivity and an important indicator of the development of acute hepatitis B to chronicity. HBeAg has a special correlation with HBV and can only be detected in HBeAg-positive serum.

HBeAg is not a structural protein of virus, nor is it involved in virus replication, but it can play an important role in the immune response after virus infection. First, as a target antigen for infected cells, HBe/cAg determinants can induce host immune responses on the surface of infected hepatocytes in synergy with human leukocyte antigen-I (HLA-1). Meanwhile, as an immunoregulatory factor, HBeAg can regulate the host's immune response, inhibit the cytotoxic activity of host T cells, and form immune tolerance to HBV infection.

In the acute phase of hepatitis B, if HBeAg remains positive for 3 months after the onset, it may be the earliest basis for the development of acute hepatitis B to chronic. A persistent positive HBeAg in chronic hepatitis indicates persistent HBV infection and is a sign of active hepatitis.

The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

Immunoassay
Today, these antigen-proteins can be genetically manufactured (e.g. transgene E. coli) to produce material for a simple antigen test, which detects the presence of HBV.

It is present in the sera of patients with viral hepatitis B (with or without clinical symptoms). Patients who developed antibodies against HBsAg (anti-HBsAg seroconversion) are usually considered non-infectious. HBsAg detection by immunoassay is used in blood screening, to establish a diagnosis of hepatitis B infection in the clinical setting (in combination w

Zecen Biotech CO., LTD., founded in 2011, is a leading Chinese diagnostics manufacturer specializing in in-vitro diagnostics devices and reagents. Zecen focus on the Chemiluminescent immunoassay (CLIA) field. With all products CE marked, our market presence currently spreads from across China to other countries including India, Switzerland, Russia etc., Zecen is expanding its footprint to become a global brand.

Zecen is the only enterprise with independent intellectual property rights in the entire chemiluminescence industry chain in China, including reagent, instrument, magnetic microbead, and reagent raw material. Our current products include more than 100 assays, from thyroid, inflammation, diabetes, tumer markers, immune disorders, hormones to cardiac markers. Our ever-expanding test menu helps our customers and collaborators keep up with the demands of healthcare sector. Zecen is striving for innovation and perfection to deliver the best products to the customers.

As a manufacturer, Zecen provide the OEM, ODM and other customized service of all products. We have the core R&D centers and innovative ability to lay a solid foundation for developing the broadest range of CLIA analyzers and test menu. High-quality sales and after-sales links provide the more intimate service. The patent and CE certification give us the confident sending all over the world, and more than 50 companys in the requiement of customized and have a long term coorperation with Zecen.